Dr Mercola Interviews Dr Villeponteau the Formulator of Stem Cell 100

Dr Bryant Villeponteau the formulator of Stem Cell 100 and other Life Code nutraceuticals was recently interviewed by Dr Mercola who owns the largest health web site on the internet. Dr. Villeponteau is also the author of Decoding Longevity a new book which will be released during December. He is a leading researcher in novel anti-aging therapies involving stem cells an area in which he has been a pioneer for over three decades.

Stem cell technology could have a dramatic influence on our ability to live longer and replace some of our failing parts, which is the inevitable result of the aging process. With an interest in aging and longevity, Dr. Villeponteau started out by studying developmental biology. If we could understand development, we could understand aging, he says. Later, his interest turned more toward the gene regulation aspects. While working as a professor at the University of Michigan at the Institute of Gerontology, he received, and accepted, a job offer from Geron Corporation a Bay Area startup, in the early 90s.

They were working on telomerase, which I was pretty excited about at the time. I joined them when they first started, he says. We had an all-out engagement there to clone human telomerase. It had been cloned in other animals but not in humans or mammals.

If you were to unravel the tip of the chromosome, a telomere is about 15,000 bases long at the moment of conception in the womb. Immediately after conception, your cells begin to divide, and your telomeres begin to shorten each time the cell divides. Once your telomeres have been reduced to about 5,000 bases, you essentially die of old age.

What you have to know about telomerase is that it’s only on in embryonic cells. In adult cells, it’s totally, for the most part, turned off, with the exception of adult stem cells, Dr. Villeponteau explains. Adult stem cells have some telomerase not full and not like the embryonic stem cells, but they do have some telomerase activity.

Most of the research currently being done, both in academia and industrial labs, revolves around either embryonic stem cells, or a second type called induced pluripotent stem cells (iPS). Dr. Villeponteau, on the other hand, believes adult stem cells are the easiest and most efficient way to achieve results.

That said, adult stem cells do have their drawbacks. While they’re your own cells, which eliminates the problem of immune-related issues, there’s just not enough of them. Especially as you get older, there are fewer and fewer adult stem cells, and they tend to become increasingly dysfunctional too. Yet another hurdle is that they don’t form the tissues that they need to form…

To solve such issues, Dr. Villeponteau has created a company with the technology and expertise to amplify your adult stem cells a million-fold or more, while still maintaining their ability to differentiate all the different cell types, and without causing the cells to age. Again, it is the adult stem cells ability to potentially cure, or at least ameliorate, many of our age-related diseases by regenerating tissue that makes this field so exciting.

Dr Villeponteau believes you can add many years, likely decades, to your life simply by eating right, exercising (which promotes the production of muscle stem cells, by the way) and living an otherwise clean and healthy lifestyle. Extreme life extension, on the other hand, is a different matter.

His book, Decoding Longevity, covers preventive strategies to prolong your life, mainly diet, exercise, and supplements. A portion of the book also covers future developments in the area of more radical life extension, such as stem cell technology.

If you would like to read the entire interview here is a link to the text version:

Click here for more information about Stem Cell 100

Transcript of Interview With Dr. Bryant Villeponteau by Dr. Joseph Mercola

Aging Reversed / ABC News

Now researchers have found a way not just to stop, but, reverse the aging process. The key is something called a telomere. We all have them. They are the tips or caps of your chromosomes. They are long and stable in young adults, but, as we age they become shorter, damaged and frayed. When they stop working we start aging and experience things like hearing and memory loss.

In a recent study published in the peer reviewed journal Nature scientists took mice that were prematurely aged to the equivalent of 80-year-old humans, added an enzyme and essentially turned their telomeres back on. After the treatment they were the physiological equivalent of young adults. You can see the before and after pictures in the videos above. Brain function improved, their fertility was restored it was a remarkable reversal of the aging process. In the top video the untreated mouse shows bad skin, gray hair and it is balding. The mouse with it’s telomeres switched back on has a dark coat color, the hair is restored and the coat has a nice healthy sheen to it. Even more dramatic is the change in brain size. Before treatment the aged mice had 75% of a normal size brain like a patient with severe Alzheimers. After the telomeres were reactivated the brain returned to normal size. As for humans while it is just one factor scientists say the longer the telomeres the better the chances for a more graceful aging.

The formal study Telomere dysfunction induces metabolic and mitochondrial compromise was published in Nature.

Additional information published by Harvard can be found in the following articles.

Scientists Find Root Molecular Cause of Declining Health in the Old

Decoding Immortality – Smithsonian Channel Video about the Discovery of Telomerase

While scientists are not yet able to accomplish the same results in humans we believe we have developed a nutraceutical to help prolong youth and possibly extend life until age reversal therapy for humans becomes available.

Stem Cells Secret’s of 115 Year Old Woman

New evidence that adult stem cells are critical to human aging has recently been published on a study done on a super-centenarian woman that lived to be 115 years. At death, her circulating stem cell pool had declined to just two active stem cells from stem cell counts that are typically more than a thousand in younger adults. Super-centenarians have survived all the normal diseases that kill 99.9% of us before 100 years of age, so it has been a mystery as to what actually kills these hardy individuals. This recent data suggest that stem cell decline may be the main contributor to aging. If so, stabilizing stem cells may be the best thing one can do to slow your rate of aging.

There are many theories of aging that have been proposed. For example, damage to cells and tissues from oxidative stress has been one of the most popular fundamental theories of aging for more than half a century. Yet antioxidant substances or genes that code antioxidant enzymes have proven largely ineffective in slowing aging when tested in model animals. Thus, interest by scientists has shifted to other hypotheses that might provide a better explanation for the slow declines in function with age.

Stem cells provide one such promising mechanism of aging. Of course, we all know that babies are young and vigorous, independent of the age of their parents. This is because adults have embryonic stem cells that can generate young new cells needed to form a complete young baby. Indeed, these embryonic stem cells are the product of continuously evolving stem cell populations that go back to the beginning of life on earth over 3.5 billion years ago!

In adults, the mostly immortal embryonic stem cells give rise to mortal adult stem cells in all the tissues of the body. These adult stem cells can regenerate your cells and tissues as they wear out and need replacement. Unfortunate, adult stem cells also age, which leads to fewer cells and/or loss of function in cell replacement. As functional stem cells decline, skin and organs decline with age.

Blood from world’s oldest woman suggests life limit

Time Magazine: Long-Life Secrets From The 115-Year-Old Woman

Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis

Abstract
The somatic mutation burden in healthy white blood cells (WBCs) is not well known. Based on deep whole-genome sequencing, we estimate that approximately 450 somatic mutations accumulated in the nonrepetitive genome within the healthy blood compartment of a 115-yr-old woman. The detected mutations appear to have been harmless passenger mutations: They were enriched in noncoding, AT-rich regions that are not evolutionarily conserved, and they were depleted for genomic elements where mutations might have favorable or adverse effects on cellular fitness, such as regions with actively transcribed genes. The distribution of variant allele frequencies of these mutations suggests that the majority of the peripheral white blood cells were offspring of two related hematopoietic stem cell (HSC) clones. Moreover, telomere lengths of the WBCs were significantly shorter than telomere lengths from other tissues. Together, this suggests that the finite lifespan of HSCs, rather than somatic mutation effects, may lead to hematopoietic clonal evolution at extreme ages.

Combat a Sedentary Lifestyle with More Time Standing

Humans are not meant to spend a great portion of their day sitting. However, a lot of people do spend even their entire days moving from chair to chair. A recent study has found that sitting can lead to a variety of health issues.

The study conducted by a team from the University of Granada (UGR), recommends that people spend more of their time standing which will help increase energy expenditure which can help them avoid health problems which are associated with a sedentary lifestyle. The study also quantifies how many extra calories a person will burn when they remain standing…45 calories more than in a sedentary state every six hours.

For the study, 53 adults were split into two groups…energy savers and energy spenders which were dependent on how much energy a person typically used when switching from lying down or sitting to standing up. While the team wasn’t quite sure why some people spend more energy than others, one factor did seem to appear to be muscle mass. The people with more muscle mass used more energy than those with less.

Energy spenders burn about 10% more energy when they switch from lying or sitting to standing. Energy savers consume very little energy in activities and the difference between lying or sitting or standing is practically nil for them.

It is really important for people to change their position. Even if a person is to get up, take 10 steps and then sit down again, it appears the effects of a sedentary lifestyle could be greatly reduced.

The research team recommends the widespread adoption of height adjustable standing desks in workplaces. These type of desks are very common in Nordic countries and the team suggests these types of desks be utilized around the globe to help reduce the risk of health issues.

The team also recommends educating school age children and young people and their teachers about the importance of avoiding long periods of time sitting down. More standing can considerably help reduce the negative consequences of sedentary lifestyle choices which can lead to obesity, excess weight and the risk of developing cardiovascular disease.

To view the original scientific study click below

Energy expenditure differences across lying, sitting, and standing positions in young healthy adults.

Drink Tea for Brain Health

Researchers at the National University of Singapore have revealed through a recent study that people who drink tea regularly have better organized brain regions compared to non tea drinkers. These brain regions are associated with healthy cognitive function and protective effects against age related decline in brain organization.

The research was conducted with collaborators from the University of Essex and the University of Cambridge. Earlier studies have shown that intake of tea is beneficial to human health and the positive effects include cardiovascular disease prevention and mood improvement. In fact, the results shown from a longitudinal study showed that daily intake of tea can reduce the risk of cognitive decline in older people by 50%.

Following these earlier studies, the team set out to further explore the direct effect tea could have on brain networks. They recruited 36 adults aged 60 and above. They gathered data about the lifestyle, health and psychological well being. They also underwent neuropsychological tests and magnetic resonance imaging (MRI). This particular study was carried out from 2015 to 2018.

After analyzing the study participant’s cognitive performance and MRI results, the team discovered that people who consumed either oolong tea, black tea or green tea at least four times per week for about 25 years, had regions of the brain that were interconnected in more efficient ways.

When the connections between regions of the brain are more structured, processing of information can be performed much more efficiently. The current results which relate to brain network indirectly support the previous findings by showing that the positive effects of regularly drinking tea are the result of improved brain organization which is brought about by preventing disruption to interregional connections.

The team plan to further examine the effects of tea as well as bioactive compounds found in tea and their effect on cognitive decline.

To view the original scientific study click below

Habitual tea drinking modulates brain efficiency: evidence from brain connectivity evaluation.

Canine Pals and Longevity

According to new research, not only do dogs give humans boundless joy and love, but can also improve mental health, and dog owners were found to live longer after suffering a stroke or heart attack. This is great news with more evidence that supports the fact that dog’s offer tangible health benefits to humans.

The new evidence comes from a meta analysis of almost 70 years of global research along with a new Swedish study of stroke and heart attack survivors spanning a decade.

The first meta analysis study drew upon data from close to 4 million people living in the U.K., the U.S., New Zealand, Canada, Australia and Scandinavia. The composite analysis included 10 studies with follow ups ranging from one year to 22 years.

It was discovered that dog ownership was associated with a 24% decrease in risk of dying by any cause and a 64% reduction in risk of death after a heart attack in particular. If a dog owner had experienced a stroke and heart attack, that person saw a 31% decrease in risk of death compared to those who experienced a cardiovascular without owning a dog.

Owning a dog was associated with lower blood pressure levels, better cholesterol profiles and increased physical exercise. All these are vital to a healthy heart.

A recent Swedish study also found that those who owned dogs lived longer and did better after suffering a stroke or heart attack. The greatest differences were found between dog non-owners and owners living in single households.

After adjusting for socioeconomic and demographic factors, this study found that the risk of death for those suffering a heart attack and who lived alone but had dogs, was 33% lower than the solitary adults who did not own dogs. Additionally, those who had suffered a stroke and lived with dogs had a 27% lower risk of death compared to those who did not have dogs.

The study analyzed data from outcomes of 182,000 people without and with dogs who had experienced a heart attack and 155,000 people after stroke. The study used health data recorded by the Swedish National Patient Register between 2001 and 2012.

Although all mechanisms can’t be confirmed since this was an observational study, the authors of the study were surprised by the large differences in the outcomes. They believe it is most likely due to exercise and companionship factors. Dogs can be great motivators for physical activity. Physical activity and social support are very important for optimal recovery after a significant cardiovascular event.

Both studies credit the additional exercise that keeping a dog entails. A recent Mayo Clinic study of 1,800 people discovered that those who had canine companions were more likely to practice heart healthy lifestyle habits such as having ideal blood sugar levels, eating well and exercising compared to those without a dog.

Researchers in the studies note that taking care of a dog or dogs also decreases depression and loneliness which can account for the added longevity among adults who live more isolated. Last year the National Poll on Healthy Aging surveyed over 2,000 adults aged 50 to 80. More than half owned a pet and 79% of the senior pet parents said their animal companion reduced stress in their lives. Among those who lived alone and/or reported fair or poor physical health, 72% remarked that their pets helped them cope with emotional and physical symptoms.

It is well known that social isolation is a significant risk factor for worse health outcomes and even premature death. Dog owners typically experience less social isolation and have more interaction with other people.

Of course dog ownership can be physically and financially demanding. A recent JAMA study showed that bone fractures related to seniors walking their dogs more than doubled between 2004 and 2017. 6% of seniors in the National Poll reported their pets caused them to fall or injure themselves. Seniors should always consider their physical limitations before adopting a pet for physical activity. Rover.com reports that dog ownership averages $153 per month so financial costs should also be taken into consideration.

To view the original scientific study click below

The power of support from companion animals for people living with mental health problems: a systematic review and narrative synthesis of the evidence

Excessive Training can make your Brain Tired

Excessive training can make the body tired, however can it make the brain tired? According to a new study, the answer is yes!

Researchers put triathletes on an excessive training load. They found they showed a form of mental fatigue. The fatigue showed reduced activity in the portion of the brain that is important for decision making. The athletes also showed more impulsive behavior, choosing immediate rewards over bigger ones that would take longer to achieve.

The lateral prefrontal portion of the brain that was affected by the overload in sport training was exactly the same which had been shown vulnerable to excessive work in earlier studies. This particular area of the brain appeared as the weak spot of the brain network which is responsible for cognitive control.

The two studies suggest a connection between physical and mental effort both of which require cognitive control. The reason for this essential control in demanding athletic training is that to maintain physical effort and to reach a distant goal, cognitive control is required. A person needs to control the automatic process that will make them stop when joints or muscles hurt.

The study originated from the National Institute of Sport, Expertise, and Performance in France which trains athletes for Olympic games. Some of the athletes suffered from over training syndrome. Their performance plummeted when they experienced an overwhelming sense of fatigue.

The question became, does this over training syndrome arise in part from neural fatigue in the brain which is the same kind of fatigue that can be caused by excessive intellectual work?

To discover the answer, the research team recruited 37 competitive male endurance athletes who had an average age of 35. The participants were assigned to either continue on with their normal training or to increase their training by 40% per session over a 3 week period.

The physical performance of the athletes was monitored during cycling exercises which were performed on rest days. The research team assessed their subjective experience of fatigue through questionnaires every 2 days. Behavioral testing and functional magnetic resonance imaging scanning experiments were also conducted.

The results showed that physical training overload caused the athletes to feel more fatigued. Additionally, they acted more impulsively in standard tests which were used to evaluate how they would make economic choices.

The tendencies were shown as a bias in favoring immediate rewards over delayed ones. The brains of the athletes who had been overloaded physically also indicated diminished activation of the lateral prefrontal cortex which is a key region of the executive control system when they made the economic choices.

The studies findings indicate that while endurance sport is generally good for health, overdoing it can lead to adverse effects on the brain. The findings bring attention to the fact that neural states matter. People don’t make the same decisions when the brain is in a state of fatigue.

The findings may be important not only for producing the best athletes, but also for economic choice theory which typically will ignore fluctuations in the neural machinery which is responsible for decision making. It also suggests it may be important to monitor fatigue levels in order to prevent bad decision making in the judicial, political and economic domains.

Future studies will explore why exerting control during sports training or intellectual work causes the cognitive control system harder to activate in subsequent tasks. The hope is to find strategies or treatments that can help prevent such neural fatigue and the following consequences.

To view the original scientific study click below

Neuro-computational impact of physical training overload on economic decision-making.

Is Air Pollution Making Us Less Intelligent?

Air pollution may have a harmful effect on more than just the heart and lungs. A new study has shown that it could also be making us less intelligent. The study conducted on elderly people living in China, has found that long term exposure to pollution in the air may hinder cognitive performance in both math and verbal tests.

As we age, the link between mental decline and air pollution becomes stronger. Evidence already shows that air pollution and even the tiniest, invisible particulates in air pollution damages the brain not only in animals but also in humans. Traffic pollution is associated with delinquent behavior in adolescents, dementia, and also stunted development of the brain in kids who attend highly polluted schools.

Almost seven million people die every year from exposure to polluted air. 91% of the world’s population lives in places where air quality exceeds WHO guideline limits. Nine out of 10 people in the world breathe air pollution. Research suggests that older men with less education were the most affected by chronic exposure to air pollution because this group of people generally work manual jobs outdoors.

When mice were exposed to urban air pollution for a period of four months they showed reduced brain function and inflammatory responses within major regions of the brain. This indicates the brain tissues changed due to response to the harmful stimuli which was produced by the air pollution.

Scientists don’t know exactly what aspects of the air pollution particulate cocktail (size, number and composition of particles) contributes most to the reported deterioration of the brain. There is evidence however that nanoscale pollution particles could be one cause.

These nanoscale particles are around 2,000 times smaller than the diameter of a single human hair. They can be moved throughout the body by the bloodstream after they are inhaled. They can even reach the brain directly from the olfactory nerves which give the brain information about smell. This allows the particles to bypass the blood brain barrier which normally protects the brain from a variety of harmful things that circulate in the bloodstream.

Brain samples from postmortem people who had been exposed to high levels of air pollution while living in Manchester, UK and Mexico City showed the typical signs of Alzheimer’s disease. This included clumps of abnormal protein fragments or plaques between nerve cells; an abundance of metal rich nanoparticles such as copper, nickle, cobalt, platinum and iron; and inflammation.

These metal rich nanoparticles found in these brains samples are found to be similar to those that are found everywhere in urban air pollution. These form from burning oil and other fuels, and wear in brakes and engines. They are very often associated with other types of hazardous compounds including polyaromatic hydrocarbons which are naturally found in fossil fuels and can lead to liver and kidney damage and also cancer.

Inhaling nanoparticles found in air pollution repeatedly may have a variety of negative effects on the brain including chronic inflammation of the nerve cells in the brain. When air pollution is inhaled, it may activate microglia, the brain’s immune cells. Breathing air pollution can constantly activate the killing response in these immune cells which can allow dangerous molecules which are known as reactive oxygen species, to form much more often. High levels of these particular molecules might cause cell damage and cell death.

The newest study showing the link between air pollution and the decline in intelligence along with the evidence already known in regards to the link between air pollution and the development of dementia, makes a case for reducing air pollution even more compelling.

Changes that include a combination of regulation and policy changes and changes to vehicle technology could provide practical ways to reduce the health burden of air pollution throughout the world.

There are a variety of things we can do to protect ourselves. Walking or cycling more and driving less can help reduce air pollution. Driving smoothly and without fierce acceleration or braking, and avoiding driving during rush hours can also help reduce emissions. Keeping car windows closed and recirculating air in the car may also help to reduce exposure to pollution during traffic jams.

Young children are the most vulnerable to health concerns with air pollution since their brains are still developing. Unfortunately, many schools are located near major roads which means a substantial reduction in air pollution is necessary. One solution to help is by planting specific tree species that are good at capturing particulates around schools and along roads.

Indoor pollution can also lead to health problems. Ventilation during cooking is needed. Open fires whether indoors or outdoors are also significant sources of particulate pollution. Wood burning stoves produce a large percentage of outdoor air pollution during the winter months. Dry, well seasoned wood should be used along with efficient ecodesign rated stoves.

Additionally, what is good for the heart is also good for the brain. Keeping the brain stimulated and active, eating a good diet which is rich in antioxidants and then keeping active and fit can help build up resistance to air pollution effects. Since it isn’t yet known exactly what mechanisms of air pollution causes damages to our brain and if their effects can be reversed, the best way a person can protect themselves is to avoid and reduce pollution exposure as much as possible.

To view the original scientific study click below

The impact of exposure to air pollution on cognitive performance.

Why We Gain Weight with Age

As we get older, it can sometimes become more difficult to keep our weight in check. New research at the Karolinska Institutet in Sweden along with collaboration with researchers at Uppsala University in Sweden and the University of Lyon in France, has discovered why this is.

During the aging process lipid turnover in our fat tissue decreases which makes it much easier for people to gain weight. This can occur even if we don’t exercise less than before or don’t eat as much.

The research team discovered the fat cells in 54 women and men turn over during an average time period of 13 years. During that time all participants, regardless of whether they lost or gained weight, showed decreases in lipid turnover in their fat tissue. This is the rate at which lipid or fat located in the fat cells is removed and stored.

Participants who didn’t compensate for this by eating less calories increased their weight by an average of 20%. These results indicate that processes in our fat tissue help regulate changes body weight during the aging process in a way that is independent of other factors.

The team also examined lipid turnover in 41 women who had bariatric surgery and how the lipid turnover rate affected the ability for them keep the weight off for 4 to 7 years following surgery.

The result indicated that only those participants who had a low rate before surgery were able to increase their lipid turnover and then maintain their weight loss. The team believe these people might have had more room for increasing their lipid turnover than the participants who already had a high level previous to the surgery.

The results could open up new treatments for obesity. Previous studies have shown that one method to speed up lipid turnover in fat tissue is to engage in more exercise. The new research does support that notion and also indicates that long term result of weight loss surgery could improve if combined with an increase in physical activity.

The majority of people who struggle with severe obesity have a prolonged struggle with their weight. Furthermore, the global problem with obesity and obesity related diseases has encouraged researchers to understand lipid dynamics and what regulates the size of fat mass.

To view the original scientific study click below

Adipose lipid turnover and long-term changes in body weight.

Metabolites Linked to Intestinal Stem Cell Function

Biologists at MIT’s Koch Institute of Integrative Cancer Research have shown that high levels of ketone bodies which are molecules produced through the breakdown of fat, help our intestines maintain a large pool of adult stem cells. These stem cells are critical for keeping the intestinal lining in our bodies healthy.

The team also found that intestinal stem cells also produce unusually high levels of ketone bodies in the absence of a high fat diet. The ketone bodies activate Notch, a well known signaling pathway. This pathway was previously shown to help regulate the differentiation of stem cells.

Ketone bodies are an example of how metabolites instruct stem cell fate within the intestines. Ketone bodies which are normally thought to perform a vital role in maintenance of energy during episodes of nutritional stress, engage the Notch pathway in order to enhance the function of stem cells. Changes in levels of ketone bodies in different diets or nutritional states enable stem cells to adapt to a variety of physiologies.

While studying mice, the team found that a ketogenic diet gave stem cells in the intestines a regenerative boost which enabled them to better recover from any damage to the lining of the intestine when compared to stem cells in the mice on a regular diet.

Adult stem cells can differentiate into a variety of different cell types and are found in tissues throughout the body. These particular stem cells are especially important in the intestine since the intestinal lining is replaced every few days. The lab had shown in previous studies that fasting will enhance stem cell function within aged mice. A high fat diet can stimulate a rapid growth of populations of stem cells in the intestine.

The team wanted to study the potential role of metabolism in the function of stem cells within the intestines. Through analyzing gene expression data, they discovered several enzymes that were involved in the production of ketone bodies to be more abundant in stem cells in the intestines than in other cell types.

When a very high fat diet was consumed, cells will use these enzymes to turn fat into ketone bodies which the body will use for fuel when carbohydrates are absent. However, these enzymes are so active in the stem cells within the intestines, they have unusually high ketone body levels even when a normal diet is consumed.

To the surprise of the team, they found the ketones stimulate the Notch signaling pathway. This is known to be critical for the regulation of stem cell functions such as damaged tissue regeneration.
Stem cells within the intestines can generate ketone bodies by themselves and then use them to sustain their own stemness by fine tuning a hardwired developmental pathway which controls stem cell fate and lineage.

By using mice, the team showed that a ketogenic diet would enhance this effect. The mice that were on this diet were better able to regenerate new tissue within the intestines. When the mice were fed a high sugar diet, they noted the opposite effect. Both stem cell function and ketone production declined.

This study helped the team answer some questions raised by previous work which showed that both a high fat diet and fasting enhance the function of intestinal stem cells. The newest findings suggest that by stimulating ketogenesis through any type of diet which limits carbohydrate intake helps promote the proliferation of stem cells.

During periods of food deprivation, ketone bodies will become highly induced within the intestine and therefore play a vital role in the process of enhancing and preserving the activity of stem cells. During times when food isn’t readily available, the intestine needs to preserve the function of stem cells so that when nutrients become replete, the body has a pool of very active stem cells which can then go on to repopulate the intestinal cells.

These findings suggest that a ketogenic diet which drives the production of ketone bodies in the intestine, could be helpful for damage repair in the lining of the intestines.

To view the original scientific study click below:

Study links certain metabolites to stem cell function in the intestine.