Dr Mercola Interviews Dr Villeponteau the Formulator of Stem Cell 100

Dr Bryant Villeponteau the formulator of Stem Cell 100 and other Life Code nutraceuticals was recently interviewed by Dr Mercola who owns the largest health web site on the internet. Dr. Villeponteau is also the author of Decoding Longevity a new book which will be released during December. He is a leading researcher in novel anti-aging therapies involving stem cells an area in which he has been a pioneer for over three decades.

Stem cell technology could have a dramatic influence on our ability to live longer and replace some of our failing parts, which is the inevitable result of the aging process. With an interest in aging and longevity, Dr. Villeponteau started out by studying developmental biology. If we could understand development, we could understand aging, he says. Later, his interest turned more toward the gene regulation aspects. While working as a professor at the University of Michigan at the Institute of Gerontology, he received, and accepted, a job offer from Geron Corporation a Bay Area startup, in the early 90s.

They were working on telomerase, which I was pretty excited about at the time. I joined them when they first started, he says. We had an all-out engagement there to clone human telomerase. It had been cloned in other animals but not in humans or mammals.

If you were to unravel the tip of the chromosome, a telomere is about 15,000 bases long at the moment of conception in the womb. Immediately after conception, your cells begin to divide, and your telomeres begin to shorten each time the cell divides. Once your telomeres have been reduced to about 5,000 bases, you essentially die of old age.

What you have to know about telomerase is that it’s only on in embryonic cells. In adult cells, it’s totally, for the most part, turned off, with the exception of adult stem cells, Dr. Villeponteau explains. Adult stem cells have some telomerase not full and not like the embryonic stem cells, but they do have some telomerase activity.

Most of the research currently being done, both in academia and industrial labs, revolves around either embryonic stem cells, or a second type called induced pluripotent stem cells (iPS). Dr. Villeponteau, on the other hand, believes adult stem cells are the easiest and most efficient way to achieve results.

That said, adult stem cells do have their drawbacks. While they’re your own cells, which eliminates the problem of immune-related issues, there’s just not enough of them. Especially as you get older, there are fewer and fewer adult stem cells, and they tend to become increasingly dysfunctional too. Yet another hurdle is that they don’t form the tissues that they need to form…

To solve such issues, Dr. Villeponteau has created a company with the technology and expertise to amplify your adult stem cells a million-fold or more, while still maintaining their ability to differentiate all the different cell types, and without causing the cells to age. Again, it is the adult stem cells ability to potentially cure, or at least ameliorate, many of our age-related diseases by regenerating tissue that makes this field so exciting.

Dr Villeponteau believes you can add many years, likely decades, to your life simply by eating right, exercising (which promotes the production of muscle stem cells, by the way) and living an otherwise clean and healthy lifestyle. Extreme life extension, on the other hand, is a different matter.

His book, Decoding Longevity, covers preventive strategies to prolong your life, mainly diet, exercise, and supplements. A portion of the book also covers future developments in the area of more radical life extension, such as stem cell technology.

If you would like to read the entire interview here is a link to the text version:

Click here for more information about Stem Cell 100

Transcript of Interview With Dr. Bryant Villeponteau by Dr. Joseph Mercola

Aging Reversed / ABC News

Now researchers have found a way not just to stop, but, reverse the aging process. The key is something called a telomere. We all have them. They are the tips or caps of your chromosomes. They are long and stable in young adults, but, as we age they become shorter, damaged and frayed. When they stop working we start aging and experience things like hearing and memory loss.

In a recent study published in the peer reviewed journal Nature scientists took mice that were prematurely aged to the equivalent of 80-year-old humans, added an enzyme and essentially turned their telomeres back on. After the treatment they were the physiological equivalent of young adults. You can see the before and after pictures in the videos above. Brain function improved, their fertility was restored it was a remarkable reversal of the aging process. In the top video the untreated mouse shows bad skin, gray hair and it is balding. The mouse with it’s telomeres switched back on has a dark coat color, the hair is restored and the coat has a nice healthy sheen to it. Even more dramatic is the change in brain size. Before treatment the aged mice had 75% of a normal size brain like a patient with severe Alzheimers. After the telomeres were reactivated the brain returned to normal size. As for humans while it is just one factor scientists say the longer the telomeres the better the chances for a more graceful aging.

The formal study Telomere dysfunction induces metabolic and mitochondrial compromise was published in Nature.

Additional information published by Harvard can be found in the following articles.

Scientists Find Root Molecular Cause of Declining Health in the Old

Decoding Immortality – Smithsonian Channel Video about the Discovery of Telomerase

While scientists are not yet able to accomplish the same results in humans we believe we have developed a nutraceutical to help prolong youth and possibly extend life until age reversal therapy for humans becomes available.

Stem Cells Secret’s of 115 Year Old Woman

New evidence that adult stem cells are critical to human aging has recently been published on a study done on a super-centenarian woman that lived to be 115 years. At death, her circulating stem cell pool had declined to just two active stem cells from stem cell counts that are typically more than a thousand in younger adults. Super-centenarians have survived all the normal diseases that kill 99.9% of us before 100 years of age, so it has been a mystery as to what actually kills these hardy individuals. This recent data suggest that stem cell decline may be the main contributor to aging. If so, stabilizing stem cells may be the best thing one can do to slow your rate of aging.

There are many theories of aging that have been proposed. For example, damage to cells and tissues from oxidative stress has been one of the most popular fundamental theories of aging for more than half a century. Yet antioxidant substances or genes that code antioxidant enzymes have proven largely ineffective in slowing aging when tested in model animals. Thus, interest by scientists has shifted to other hypotheses that might provide a better explanation for the slow declines in function with age.

Stem cells provide one such promising mechanism of aging. Of course, we all know that babies are young and vigorous, independent of the age of their parents. This is because adults have embryonic stem cells that can generate young new cells needed to form a complete young baby. Indeed, these embryonic stem cells are the product of continuously evolving stem cell populations that go back to the beginning of life on earth over 3.5 billion years ago!

In adults, the mostly immortal embryonic stem cells give rise to mortal adult stem cells in all the tissues of the body. These adult stem cells can regenerate your cells and tissues as they wear out and need replacement. Unfortunate, adult stem cells also age, which leads to fewer cells and/or loss of function in cell replacement. As functional stem cells decline, skin and organs decline with age.

Blood from world’s oldest woman suggests life limit

Time Magazine: Long-Life Secrets From The 115-Year-Old Woman

Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis

Abstract
The somatic mutation burden in healthy white blood cells (WBCs) is not well known. Based on deep whole-genome sequencing, we estimate that approximately 450 somatic mutations accumulated in the nonrepetitive genome within the healthy blood compartment of a 115-yr-old woman. The detected mutations appear to have been harmless passenger mutations: They were enriched in noncoding, AT-rich regions that are not evolutionarily conserved, and they were depleted for genomic elements where mutations might have favorable or adverse effects on cellular fitness, such as regions with actively transcribed genes. The distribution of variant allele frequencies of these mutations suggests that the majority of the peripheral white blood cells were offspring of two related hematopoietic stem cell (HSC) clones. Moreover, telomere lengths of the WBCs were significantly shorter than telomere lengths from other tissues. Together, this suggests that the finite lifespan of HSCs, rather than somatic mutation effects, may lead to hematopoietic clonal evolution at extreme ages.

Lower Cancer Risk Through Early Morning Exercise

A new study has revealed that people who exercise in the morning between 8:00 a.m. and 10:00 a.m. as opposed to later in the day may be less likely to develop certain types of cancer. This new research may help future research into the timing of exercising as a possible way to reduce the risk of cancer.

Previous research has shown that recreational exercise can reduce the risk of developing many types of cancers. This is important because of the high incidence of people developing cancer and the significant number of people who die from their disease. In the United States, it is estimated that by the end of 2020 1,806.590 people will be diagnosed with cancer while 606,520 people will die from cancer.

With the large number of people developing cancer, any small changes even as small as changing the time of day for exercising could make a significant contribution to the reduction of cancer across an entire population.

The recent study by researchers from the Barcelona Institute of Global Health and the Department of Epidemiology at the Medical University of Vienna studied the exercise habits of 2,795 participants. The participants were a subset of the Spanish multi-case control study that set out to understand factors that cause common cancers in Spain and additionally how to prevent them.

From 2008 to 2013 the team interviewed the participants to learn about their household physical activity and their lifetime recreational activity. At about 3 years later, the team assessed the timing of when the participants exercised. They looked in particular at 781 women with breast cancer and who had responded to the questionnaire about their physical activity and 504 men with prostate cancer who had provided data about the timing of their exercise.

The controls in the study were chosen randomly from general practice records. The team matched them to people in the study with cancer who were of similar age and the same sex. The controls also responded to the follow-up questions in regards to their physical activity and their timing.

The team discovered that people who exercised between 8:00 a.m. and 10:00 a.m. had the strongest possible beneficial effect at reducing prostate and breast cancer. About 7% of the women with breast cancer and 9% of people in the control group engaged in their exercise in early morning. About 12.7% of the men with prostate cancer and 14% of that control group also engaged in early morning exercise.

The team developed a model that showed that early morning exercise was associated with a 25% lower risk of breast cancer and a 27% lower risk of prostate cancer. Similarly, people who exercised in the evening between 7:00 p.m. and 11:00 p.m had a 25% reduced risk for developing prostate cancer.

The research suggests that any benefits to early morning exercise for the risk of breast cancer may have links to estrogen. High levels of estrogen have links to an increased risk of breast cancer and exercise can lower levels of estrogen. Estrogen production is most active around 7:00 a.m.

Melatonin might also be a factor. Research has shown that melatonin may protect against cancer risk and exercise later in the day or at night can delay the production of melatonin.

The team does note that the study has limitations, and they could not detect the small effect the timing of exercise may have with certainty. However, this does not mean it is not important. Cancer is a prolific disease and even small effects when amplified throughout a population can be important.

Regardless, the study clarifies the value of further exploration into the association between the timing of exercise and the risk of cancer. What is clear is that anyone can help reduce their risk of developing cancer by simply engaging in moderate physical activity for at least 150 minutes a week. Exercise is critically important for a variety of reasons. It helps people have more energy, helps them feel better and at affects a variety of biological processes that may themselves reduce the risk of cancer.

To view the original scientific study click below

Effect of time of day of recreational and household physical activity on prostate and breast cancer risk (MCC?Spain study)

Blue Light Filtering Glasses Improve Workday Productivity and Sleep

New research has shown that by wearing blue-light glasses right before sleeping a person can get a better night’s sleep and also contribute to better workday productivity. This is especially important since people are learning and working from home as well as binge watching TV more than ever before due to the pandemic.

The team discovered that wearing blue-light filtering glasses is an effective way to not only improve sleep but also task performance, work engagement and organizational citizenship behaviors. It also reduced counterproductive work behavior. These glasses create a form of physiologic darkness which leads to improved sleep quality and quantity.

Most of the technology people use such as smartphones, computer screens, and tablets all emit blue light. Past research has shown that these devices through the blue light they emit can disrupt sleep. As we currently navigate school and work, people have become more dependent on these devices.

The new research has helped extend the understanding of the circadian rhythm which is a natural, internal process that regulates our sleep/wake cycle and repeats approximately every 24 hours. Before modern times people were not exposed to blue light after the sunset. Wearing blue light filtering glasses produces a similar effect. To get the best results the glasses should be worn starting about two hours before going to bed and until the lights in the bedroom are turned off. Some people put them on right after it gets dark.

Generally speaking, the effects of wearing blue-light filtering glasses are stronger for night owls as opposed to morning larks. Night owls tend to sleep during later times in the day while larks tend to sleep earlier in the day.

Although most anyone can benefit from reducing their exposure to blue light, night owl employees seem to benefit more as they encounter greater misalignments between their internal clock and the externally controlled work time. The team’s research highlights how and when wearing the blue-light filtering glasses can help employees to live better and work better.

The team’s research discovered that daily engagement of task performance may be related to underlying processes such as the circadian process. The research pushes the chronotype literature to think about the relationship between employees’ performance and the timing of circadian processes.
A good night’s sleep will not only benefit workers, it will also help their employer’s bottom lines.

Through two studies, the team collected data from 63 company managers and 67 call center reps at Brazil based offices for a United States multinational financial firm and measured task performance from clients. The participants were randomly chosen to test blue-light filtered glasses or those that were placebo glasses.

Employees can often be required to work early mornings which can lead to a misalignment between the externally controlled work time and their internal clock. The team found that their analyses showed a general pattern that blue-light filtration can have a cumulative effects on key performance variables at least in the short term.

They note that blue-light exposure should be a concern to organizations. The ubiquity of this phenomenon suggests that blue-light exposure control might be a viable first step to protect the circadian cycles of their employees from disruption.

To view the original scientific study click below

The effects of blue-light filtration on sleep and work outcomes.

Why Average Body Temperature has Dropped in Healthy Adults

Almost two centuries ago the standard “normal” body temperature in humans was established at 98.6 degrees Fahrenheit and has been used as the measure for assessing fevers. However, over time lower body temperatures have been widely reported in healthy adults.

A study conducted in 2017 among 35,000 adults in the U. K. found average body temperatures to be lower at 97.9F and a study in 2019 in the U. S. found normal body temperatures at about 97.5F.

Interestingly, recent studies in both the U. S. and the U. K. have found a similar decrease among the Tsimane which is an indigenous population of forager horticulturists located in the Bolivian Amazon. A team that has been observing this population have observed a rapid decline in body temperature of 0.09 degrees Fahrenheit such that today this population’s body temperatures are about 97.7F.

In less than two decades researchers are seeing the same levels of decline as that which has been observed in the U. S. over about two centuries. The analysis is based on a large sample of 18,000 observations of about 5,500 adults with adjustments for factors that can affect body temperature such as body mass and ambient temperature.

It is clear that something about human physiology has changed. The researchers leading hypothesis is that we have experienced fewer infections over time due to clean water, improved hygiene, medical treatment and vaccinations. In the recent study, they were able to test these ideas directly. They have information on clinical diagnosis and also biomarkers of inflammation and infection at the time each patient was seen.

Although some infections were associated with high body temperatures, adjusting for those did not account for the steep decline in temperatures over time. The same type of thermometer was used for most of the study so the changes were not due to changes in instruments.

No matter how they did the analysis, the declines were still there. Even when they restricted analysis to less than 10% of adults who were diagnosed as completely healthy, they still observed the same decline in body temperatures over time.

A key question became then is why body temperatures have declined in both Americans and the Tsimane population. Data available from the team’s long-term research in Bolivia addressed some of the possibilities. Declines could be due to the rise of modern health care and lower incidences of lingering mild infections compared to the past. However, while health has improved over the past two decades, infections are still widespread in rural areas of Bolivia. This then suggests that reduced infection alone isn’t why the decline in body temperatures.

It may be that people are in general in better condition which means their bodies could be working less to fight infection. Greater access to antibiotics and other medical treatments means that the duration of infections is shorter now than was in the past. The team did find that respiratory infection in the early period of the study led to having a high body temperature than having the same infection more recently.

Another possible explanation is that our bodies don’t have to work as hard to regulate our internal temperature due to air conditioning in the summer and heating in the winter. Although Tsimane body temperatures will change with time of year and patterns of the weather, these people do not use any advanced technology for helping to regulate their body temperature. They do however, have more access to blankets and clothes.

The research team was initially surprised to find no single magic bullet that would explain the decline in body temperature. They believe it is likely due to a combination of factors which all point to improved conditions.

Temperature as a vital sign is an indicator of what is occurring physiologically inside the body. One thing that has been known for a while is that there is not universal body temperature for everyone at all times. Despite the fixation on 98.6F, most clinicians know that normal temperatures have a range and throughout the day, temperatures can vary by as much as 1 degree Fahrenheit from lowest in early morning to its highest in the late afternoon. It will also vary following physical activity, across the menstrual cycle, and tends to decrease with age.

Through linking improvements in the broader epidemiological and socioeconomic landscape to body temperature changes, the study does suggest that information in regards to body temperature may provide clues to a population’s overall health along with other common indicators such as life expectancy. Since body temperature is easy to measure, it can easily be added to routine large-scale surveys that monitor the health of populations.

To view the original scientific study click below

Rapidly declining body temperature in a tropical human population.

Positive Outlook and Less Memory Decline

A new study has shown that people who are cheerful and feel enthusiastic or what is known as the “positive effect”, are less likely to experience decline in memory with aging. This study adds to a growing body of research that shows the role a positive outlook has on aging.

Many of wish some of our memories could last a lifetime. However, emotional and physical factors can negatively impact our ability to retain information throughout our life.

The research team analyzed data from 991 older and middle aged adults in the United States who had participated in a national study conducted at three different time periods – 1995 and 1996, 2004 and 2006, and 2013 and 2014.

With each assessment, participants reported on a range of positive emotions they experienced during the previous 30 days. In the last two assessments, they also completed tests of memory performance. These tests involved participants recalling words immediately following their presentation and again 15 minutes later.

The team then examined the association between positive effect and memory decline. They accounted for gender, age, education, negative effect, depression and extroversion.

The findings indicated that memory did decline with age. However, participants with higher levels of positive effect had a less steep memory decline over the period of almost a decade.

Future research will look at addressing the pathways that could connect memory and positive effect such as social relationships and physical health.

To view the original scientific study click below

Positive Affect Is Associated With Less Memory Decline: Evidence From a 9-Year Longitudinal Study

Hair Loss and Regulating Stem Cell Metabolism

New research has identified a mechanism that appears to be able to prevent hair loss. A group of researchers in Helsinki and Cologne Germany have demonstrated that a protein known as Rictor holds a key role in the process.

Hair follicle stem cells promote hair growth and can also prolong their life by switching their metabolic state. Environmental factors such as ultraviolet radiation damage our skin and other tissues daily. The body continuously removes and renews the damaged tissues. Human sheds about 500 million cells daily and a quantity of hairs weighing a total of 1.5 grams.

Dead material is replaced through specialized stem cells that promote tissue growth. The function of tissues is dependent on the health and activity of these stem cells. Impaired activity will result in the aging of the tissues.

The critical role of stem cells and aging has been established, however little is known about the mechanisms that regulate long-term maintenance of these vital cells. The hair follicle which is well understood and has clearly identifiable stem cells is the prefect model system for researchers to study this question.

At the end of a hair follicle’s regenerative cycle and when a new hair is created, stem cells return to their specific location and resume a quiescent state. The most important finding in the research team’s study is that the return to the stem cell state requires a change in the cell’s metabolic state. The cells switch from glutamine based metabolism and cellular respiration to glycolysis. This is a shift triggered through a signal that is induced by the Rictor protein in response to the low oxygen concentration in the tissue. The study demonstrated that the absence of this protein impaired the reversibility of the stem cells. This initiated a slow exhaustion of the stem cells and loss of hair due to aging.

The team created a genetic mouse model for the purpose of studying the Rictor protein. They observed that hair follicle regeneration and cycle were delayed quite significantly in mice who lacked the protein. Older mice suffering from a deficiency of this protein showed a gradual decrease in their stem cell which resulted in hair loss.

Additional research will be conducted to investigate how the pre-clinical findings might be utilized in human stem cell biology and also lead to drug therapies that would protect hair follicles from aging. The mechanisms found in the recent study might possibly be utilized in preventing loss of hair.

The team was most exited about their observation that the application of a glutaminase inhibitor was able to restore function of the stem cells in the Rictor deficient mice. This proved the principle that by modifying metabolic pathways, a powerful way to boost the regenerative capacity of our tissues occurred.

To view the original scientific study click below

Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle

Brain Circuit Damage Due to Childhood Social Isolation

A research team at the Icahn School of Medicine at Mt. Sinai have identified specific sub-populations of brain cells located in the prefrontal cortex that are required for normal sociability in adulthood and are also profoundly vulnerable to social isolation in juvenile mice. The prefrontal cortex in the brain is a key part of the brain that regulates social behavior. The study conducted on mice shows long lasting effects and also directs the way to potential treatments.

Loneliness and isolation are both recognized as serious threats to mental health. Young people are feeling a growing sense of isolation even as the world becomes increasingly connected through digital platforms. The COVID-19 pandemic which has forced many countries around the world to implement school closures and social distancing, increases the need for better understanding of the mental health consequences of loneliness and social isolation.

Research has shown that social isolation during childhood is detrimental to adult brain function and behaviors across mammalian species. However, the underlying neural circuit mechanisms are poorly understood.

The research team’s discovery sheds light on a previously unrecognized role of the sub-populations of brain cells in the prefrontal cortex. These cells are known as medial prefrontal cortex neurons projecting to the paraventricular thalamus which is the area of the brain that relays signals to various components of the brain’s reward circuitry. If the team’s findings can be replicated in humans, it could lead to treatments for psychiatric disorders that are connected to isolation.

The team also demonstrated that the vulnerable circuit they identified is a promising target for treatments for deficits in social behaviors. By stimulating the specific prefrontal circuit projecting to the thalamic area in adulthood, they were able to rescue sociability deficits caused by social isolation during the juvenile years.

The team found that in male mice two weeks of being socially isolated immediately following weaning led to a failure to activate medial prefrontal cortex neurons projecting to the paraventricular thalamus during social exposure in adulthood. They discovered that juvenile isolation led to not only reduced excitability of the prefrontal neurons projecting to the paraventricular thalamus, but also increased inhibitory input from other related neurons. This suggests that a circuit mechanism underlies sociability deficits caused by juvenile isolation.

In order to determine if acute restoration of the activity of the prefrontal projections to the paraventricular thalamus is sufficient to ameliorate sociability deficits in adult mice that had been put under juvenile social isolation, the researchers employed a technique known as optogenetics to selectively stimulate the projections to the thalamus.

In addition, they used chemogenetics in the study which enabled them to stimulate particular neurons in freely moving animals through pulses of light. Chemogenetics allows non-invasive chemical control over populations of cells.

By employing both techniques, the team was able to quickly increase social interaction in the mice once light pulses or drugs were given to them. The team checked the presence of social behavior deficits just before stimulation and when they checked the behavior while the stimulation was going on, they found that the social behavior deficits were reversed.

Since social behavior deficits are a common characteristic of many neurodevelopmental and psychiatric disorders such as schizophrenia and autism, identification of these specific prefrontal neurons will point towards therapeutic targets for the improvement of social behavior deficits that are shared across a range of psychiatric disorders. The circuits that were identified in this study could potentially be modulated through techniques like transcranial magnetic stimulation and/or transcranial direct current stimulation.

To view the original scientific study click below

A prefrontal–paraventricular thalamus circuit requires juvenile social experience to regulate adult sociability in mice. Nature Neuroscience, Aug. 31, 2020; DOI: 10.1038/s41593-020-0695-6

Nano-Particles and Effects on Health

Nano-particles can be useful and even valuable in a variety of products, however according to a recent study they can also damage our cells. Researchers are now concerned about the effects of lifelong exposures to this human organism.

Nano-particles are used in a wide variety of manufacturing processes and products. This is due to the fact that the properties of a material can dramatically change when that material comes down in nano form.

These particles are used to transport medicine around the body and to purify wastewater. They are also added to pillows, socks, phone covers, mattresses and refrigerators which supplies these items with an antibacterial surface.

A large amount of research has been conducted on how nano-particles affect the environment and humans. Some studies have shown that nano-particles can damage or disrupt human cells. This has been recently confirmed by the new study that also studied how cells react when they have been exposed to more than one type of nano-particle at the same time.

We are exposed to many different kinds of nano-particles throughout our lifetime. The research team involved with the new study set out to investigate how the combination of different nano-particles can affect us and in addition whether an accumulation throughout a life can harm us.

In the new study, the team looked at nano-platinum and nano-silver. They not only looked at the individual effect but also whether exposure to both types result in a synergy effect in two types of cells in the brain.

Nano-silver was chosen because it is already known to be able to damage cells and nano-platinum because it is considered to be a bio-inert which means it has a minimal interaction with human tissue.

Both nano-particles were tested on two types of cells found in the brain – astrocytes and endothelial cells. Astrocytes are supporter cells found in the central nervous system which helps in supplying the nervous system with nutrients and repair brain damage. Endothelial cells reside on the inside of the blood vessels and transport substances from the bloodstream to the brain.

When the team exposed endothelial cells to nano-platinum nothing happened. When they were exposed to nano-silver their ability to divide resulted in deterioration. When the cells were exposed to both nano-platinum and nano-silver, the resulting effect amplified and large numbers of the cells died. Additionally, their defense mechanisms decreased and they also had difficulty communicating with each other.

Even though nano-platinum by itself did no harm, something drastic happened when they were combined with a different kind of nano-particle. The astrocytes were hardy and only reacted with impaired ability to divide when they were exposed to both nano-platinum and nano-silver.

An earlier study has shown a dramatic synergy effect of nano-silver and cadmium ions which are naturally found all around us on earth. This study showed that 72% of cells in the intestine died when they were exposed to both nano-silver and cadmium ions. When these cells were exposed to just
nano-silver 25% died. When exposed to cadmium ions alone, 12% died.

Unfortunately, little is known about how large concentrations of nano-particles are used in industrial products. It is also not known what size particles are used. Size has also shown an effect on whether they can enter a cell. What we do know is that many people are involuntarily exposed to nano-particles and there can easily be lifelong exposure.

Currently there are no restrictions on adding nano-particles to products. However, in the EU manufacturers must have approval if they want to use nano-particles in products that have antibacterial properties and in Denmark, they must also declare nano-contact on product labels containing them.

To view the original scientific study click below

The Cytotoxicity of Metal Nanoparticles Depends on Their Synergistic Interactions