Stem Cell Support for Restful Sleep, Stress Reduction, Healthy Adrenals and Healthy Cortisol Levels

Advanced Calm


Advanced Calm Options




The everyday stress of modern life ages us and so does poor sleep. Advanced CalmTM is our patent-pending nutraceutical supplement that helps to support the adrenal system, reduce stress, decrease anxiety, improve sleep, increase energy, and maintain healthy cortisol levels.

Our modern high stress life style can lead to deregulated cortisol cycles, further increasing stress, fatigue, and poor sleep. These problems become even greater as we age and they age us faster. Advanced CalmTM provides help both during the day and night without causing any day time drowsiness.

Developed by experts in the anti-aging field, Advanced CalmTM was created using genetic and computer intelligence systems to select natural substances that support longevity, adult stem cells, and organ health with age.

Promote Better Adrenal Function With the Power of Your Own Stem Cells

All organ systems have their own reservoirs of adult stem cells. Unfortunately, as we are exposed to modern stress and as we age most adult stem cell populations either decline in number and/or lose the ability to differentiate into functional tissue-specific cells. For example, in many critical organs old folks have only half the number of stem cells found in young people. Thus, adult stem cells become more and more dysfunctional, so that organ and tissue dysfunction increases with age.

The Many Benefits of Advanced CalmTM

1. Promotes adult stem cell growth and neurogenesis [1-6] and stem cell factor [7].
2. Improves adrenal function and reduces cortisol levels [2,8-12]
3. Reduces stress and anxiety [3,8-10,12-33]
4. Promotes restful sleep [22,34-47]
5. Promotes cognitive performance and mood [6,30,46,48-53]
6. Fights fatigue and promotes stamina [54-56]
7. May reduce blood pressure for those already in the normal range [26,57-61]
8. May reduce LDL cholesterol for those already in the normal range[62-64] and blood vessel wall thickness [65]
9. May improve sexual function and fertility levels [66-69]
10. May extend lifespan [70,71]
11. Helps promote the immunes system [72,73]

Advanced CalmTM Formulation and Use

Serving Size: One type 00 capsule

Servings Per Container: 60 Capsules

Recommended Use: Typical usage of Advanced CalmTM is one or two capsules per day, preferably just before bed time. Since Advanced CalmTM is a potent formulation, start off with one capsule per day and try taking two capsules per day after 3 or 4 days if you have not experienced significant stress reduction or restful sleep.

 


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Active Ingredients: There are 8 natural components that make up the patent-pending combination in Advanced CalmTM. The herbal components are highly extracted natural herbs that are standardized for active components that promote adrenal function, adult stem cells, higher quality of sleep, and lower stress:

1) Withania somnifera (aka Ashwagandha) is the principle adaptogen in Indian Ayurvedic Medicine (IAM) that has been shown to reduce chronic stress via modulation of Cortisol and neurotransmitters, which has positive effects on stem cells, telomeres, and the several hormone secreting organs. Unlike American and Asian ginseng adaptogens, Withania has rebalancing and energy promoting effects without raising blood pressure. Life Code? uses a high quality proprietary IAM Withania somnifera extract that tests well in our stem cell screening experiments.

2) Schisandra chinensis berry extract has been important in Chinese traditional medicine as an “adaptogen” for stress resistance, longevity, and increasing energy, physical performance, and endurance. Schisandra extracts reduce TNF-alpha, IL-1B, IL-6, Abeta, and cortisol to suppress neural inflammation. Schisandra also induces the protective Nrf2 and HO-1 genes to promote cholinergic signaling. These pathways are all strongly linked to longevity in our genetic and machine-learning screens and to stress though the current literature.

3) L-Theanine is a natural amino acid from Camellia sinesis that reduces mental stress and inflammation while improving cognition and protecting brain cells from ischemic or toxic injury. L-theanine alters novel longevity and stress genes identified in our genetic and machine-learning screens. Among its psychoactive properties, L-Theanine is reported to reduce metal stress and improved cognition and mood via its expected binding to the GABA brain receptors in the parasympathetic nervous system. Thus L-Theanine appears to increase the overall level of the brain inhibitory transmitter GABA and is reported to promote alpha wave production in the brain. L-Theanine also increases brain dopamine concentrations and has significant affinities for the AMPA, Kainate, and NMDA receptors.

4) Lemon Balm leaves are often used for their calming effects to promote sleep and reduce stress and anxiety. Traditionally, the herb has also been taken for indigestion, infections, mood disorders, menstrual cramps, and blood pressure.

5) Epimedium koreanum aerial parts (aka Horney Goat Weed) act as a general tonic with aphrodisiac effects. The main standardized component in our our Epimedium extract is icariin, which increases blood flow to the body organs by targeting PDE-5 and Nitric Oxide. Epidmedium extracts have often been used to support the immune system and sexual and cognitive performance. Life Code? uses a high quality proprietary Epimedium koreanum extract that tests well in our stem cell screening experiments.

6) Valerian root is most commonly used in combination with Lemon Balm for sleep disorders. This complex herb is calming without the handover of more potent sedatives. Beside its anti-anxiety effects, other uses have included muscle or uterine cramps, and muscle relaxant for pain relief.

7) Magnolia bark is an herb that has been utilized to support healthy cortisol levels while reducing anxiety and stress. It also has benefits for abdominal pain, indigestion, LDL cholesterol, and vascular health.

8) Pregnenolone is a natural hormone that is primarily manufactured by the adrenal glands. Pregnenolone is the precursor for DHEA and Progesterone which are precursors to all other hormones. With age, these hormones often decline with age, leading to lower energy levels and problems with anxiety, cognition, and sleep quality. Pregnenolone supplements can provide needed hormone replacement and is generally available in capsules ranging from 10 mg up to 100 mg. Advanced CalmTM uses very low 3 mg servings of Pregnenolone which is a very conservative amount yet can make a big difference in results compared to other adrenal, cortisol and stress supplements on the market which do not contain any. Even taking the recommended highest dose of Advanced CalmTM only gives 6 mg, which is a little over half of the common 10 mg or higher doses found in normal Pregnenolone supplements. Since Pregnenolone accumulates taking 3 mg – 6 mg per day is a better serving size for long term use.

Safety: The eight components in Advanced CalmTM are nutraceutical grade and have been individually tested in both animals and humans without significant safety issues. Advanced CalmTM is produced using cGMP (Good Manufacturing Practices) in FDA certified production facilities and each batch lot is independently lab tested for harmful microorganisms and toxic metals. This nutraceutical supplement is not recommended for pregnant or lactating women.

References:TM

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These statements have not been evaluated by the Food and Drug Administration. Advanced CalmTM is not intended to diagnose, treat, or prevent any disease.

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